Twelve
VideosDisclaimer:
Individual results vary. Anti-TNF treatment for the indications
below is off-label. Please see the Legal Disclaimer. Adverse reactions may occur.
Some patients do not respond. Maintenance dosing, usually weekly,
but sometimes as little as monthly, is necessary for optimal effect.
The methods of anti-TNF treatment utilized for these patients
are patented inventions of the INR[1].Please click directly
on the play button of the twelve
videos below to view each
movie within this webpage. Additional
videos are available in large,
high quality versions on this website. Please take the time
to view each of the videos, filmed over a period of more than
three years, because each includes new information, documenting
improvement in patients with mild, moderate, and severe Alzheimer's,
including both rapid and sustained improvement.Rapid improvement in speech following anti-TNF
initiation at the INR (2008)* video
length 4:59
Rapid improvement in speech
in primary progressive aphasia following perispinal etanercept.
For the published results please see Perispinal etanercept
produces rapid improvement in primary progressive aphasia: identification
of a novel, rapidly reversible TNF-mediated pathophysiologic mechanisms.
Edward Tobinick MD. Medscape Journal of Medicine, Neurology
and Neurosurgery Clinical Cases 2008 June 10; 10(6):135. This
video was included as part of the peer-reviewed, published, scientific
article.From Australia for perispinal
etanercept treatment at the INR in Los Angeles: (2009)* video length 15:47 min.
The story of a husband
and wife who traveled from Melbourne, Australia for treatment
of Alzheimer's disease utilizing the unique perispinal etanercept
treatment invented at the Institute for Neurological Research®
(INR®) in Los Angeles. Before and after video, testing, and
interview with the patient's wife. Please see
Perispinal etanercept
for neuroinflammatory disorders.
Edward Tobinick MD. Drug
Discovery Today 2009 Feb; 14(3-4):168-77.Sustained
improvement through one year following perispinal etanercept (2009)*
video length 3:53
This video was filmed
in Los Angeles in February 2009, and includes an interview of
the patient and her daughter, who have been flying to the INR®
in Los Angeles from Oklahoma on a regular basis for perispinal
etanercept treatment for Alzheimer's. Both mother and daughter
have recently been featured on a TV news piece which was seen
across the country, discussing their positive and sustained results.
Please see Perispinal etanercept for neuroinflammatory disorders. Edward
Tobinick MD. Drug Discovery Today 2009 Feb; 14(3-4):168-77.Rapid improvement within minutes and sustained
improvement following perispinal etanercept in Alzheimer's disease
(2007)* video length 6:22
This video is actual patient
footage showing the patient's clinical improvement within minutes
following initiation of perispinal etanercept at the INR, and
his sustained response through five weeks. This video is a companion
to the published editorial entitled Perispinal etanercept:
potential as an Alzheimer therapeutic. Griffin WS. Journal
of Neuroinflammation 2008 January; 5:3.Rapid
improvement within minutes following perispinal etanercept administration
(2007)* video length 6:47
min.
This video is an interview
with a physician and his two family members documenting and discussing
the response to initiation of perispinal etanercept at the INR.
For the published results please see Rapid cognitive improvement
in Alzheimer's disease following perispinal etanercept administration.
Edward Tobinick MD, Hyman Gross MD. Journal of Neuroinflammation
2008 January; 5:2.Son discussing
his father's rapid and significant clinical improvement (2005)*video length 3:49
This video is an interview
with a son discussing his father's clinical response to initiation
of perispinal etanercept at the INR. For the published results
please see TNF-alpha Modulation for Treatment of Alzheimer's
Disease: A 6-Month Pilot Study. Tobinick E, Gross H, Weinberger
A, Cohen H. MedGenMed 2006; 8(2) :25.Wife
(social worker) discussing rapid improvement following perispinal
etanercept for Alzheimer's (2005)*video length 5 min.
This video is an interview
with a social worker discussing her ex-husband's clinical response
to initiation of perispinal etanercept at the INR. For the published
results please see TNF-alpha Modulation for Treatment of
Alzheimer's Disease: A 6-Month Pilot Study. Tobinick E,
Gross H, Weinberger A, Cohen H. MedGenMed 2006; 8(2) :25.Sustained improvement through one year following
perispinal etanercept (2009)* video
length 2:39
This video was filmed
in Los Angeles in February 2009 and August and September 2008,
and includes an interview of the patient and her daughter. Please
see Perispinal
etanercept for neuroinflammatory disorders. Edward
Tobinick MD. Drug Discovery Today 2009 Feb; 14(3-4):168-77.Sustained improvement through six months following
perispinal etanercept (2009)* video
length 3:18
This video, filmed at
the INR® in Los Angeles February 26, 2009, documents the many
improvements sustained through the first six months of treatment
with perispinal etanercept (PSE) in a patient with Alzheimer's
disease, as seen by the patient's family. Please see Perispinal
etanercept for neuroinflammatory disorders. Edward
Tobinick MD. Drug Discovery Today 2009 Feb; 14(3-4):168-77."Now she's eating solid food": sustained
improvement (2009)* video
length 3:09
The patient's daughter-in-law
documents the improvements sustained through the first five months
of treatment with perispinal etanercept (PSE) in a patient with
severe dementia who flew to the INR from Hawaii for treatment.
Please see Perispinal etanercept for neuroinflammatory disorders. Edward
Tobinick MD. Drug Discovery Today 2009 Feb; 14(3-4):168-77.Sustained improvement through 46 months with
perispinal etanercept (2009)* video
length 2:01
This video, filmed at
the INR® in Los Angeles in March 2009, is of a 91 y.o. who
remains better than baseline through 46 months of perispinal etanercept
treatment. Please see Perispinal etanercept for neuroinflammatory
disorders. Edward Tobinick MD. Drug Discovery Today
2009 Feb; 14(3-4):168-77."I've
seen a very remarkable change" [with perispinal etanercept]
(2008)* video length 4:16
This video, filmed at
the INR® in Los Angeles during 2008, documents the many improvements
sustained through the first year of treatment with perispinal
etanercept (PSE) in a patient with severe, early onset dementia,
as related by the patient's wife. Please see
Perispinal etanercept
for neuroinflammatory disorders.
Edward Tobinick MD. Drug
Discovery Today 2009 Feb; 14(3-4):168-77.The videos above are interviews discussing
and documenting the clinical response to initiation of anti-TNF
treatment (perispinal etanercept) at the INR. For the published
results please see Tobinick E, Gross H, Weinberger A, Cohen H.,
TNF-alpha Modulation for Treatment of Alzheimer's Disease:
A 6-Month Pilot Study MedGenMed 2006; 8(2) :25; Tobinick
E., Perispinal etanercept for treatment of Alzheimer's disease,
Current Alzheimer Research 2007 Dec; 4(5):550-2; Tobinick
E, Gross H., Rapid improvement in verbal fluency and aphasia
following perispinal etanercept in Alzheimer's disease, BMC
Neurology 2008; 8:27; and Tobinick E., Perispinal etanercept
for neuroinflammatory disorders, Drug Discovery Today
2009 Feb; 14(3-4):168-77.Institute
for Neurological Research, a
private medical group, inc.
100 UCLA Medical Plaza, Suites 205-210 Los Angeles, California
90095
