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Disclaimer: Individual results vary. Anti-TNF treatment for the indications below is off-label. Please see the Legal Disclaimer. Adverse reactions may occur. Some patients do not respond. Maintenance dosing, usually weekly, but sometimes as little as monthly, is necessary for optimal effect. The methods of anti-TNF treatment utilized for these patients are patented inventions of the INR**.
Please click directly on the Flash® videos below to view their contents within this webpage. Hint: if your internet connection is slow, please place the video on pause and allow it to download before playing for best playback quality. If you still have trouble viewing the video correctly, then please visit the INR Videos webpage with smaller version videos

Video 1: Rapid improvement within minutes and sustained improvement through five weeks following perispinal etanercept in Alzheimer's disease*


This video is actual patient footage showing the patient's clinical improvement within minutes following initiation of perispinal etanercept at the INR, and his sustained response through five weeks. This video is a companion to the published editorial entitled Perispinal etanercept: potential as an Alzheimer therapeutic. Griffin WS. Journal of Neuroinflammation 2008 January; 5:3.
Video 2: Rapid cognitive improvement in Alzheimer's disease within minutes following perispinal etanercept administration*


This video is an interview with two family members discussing their family member's clinical response to initiation of perispinal etanercept at the INR. For the published results please see Rapid cognitive improvement in Alzheimer's disease following perispinal etanercept administration. Tobinick E, Gross H. Journal of Neuroinflammation 2008 January; 5:2. This video was included as part of the peer-reviewed, published, scientific article.
Video 3: Anti-TNF for Alzheimer's Disease, rapid and significant clinical improvement*


This video is an interview with a family member discussing his family member's clinical response to initiation of perispinal etanercept at the INR. For the published results please see TNF-alpha Modulation for Treatment of Alzheimer's Disease: A 6-Month Pilot Study. Tobinick E, Gross H, Weinberger A, Cohen H. MedGenMed 2006; 8(2) :25 .
Video 4: Rapid improvement in speech following anti-TNF initiation at the INR*


Rapid improvement in speech in primary progressive aphasia following perispinal etanercept. For the published results please see Perispinal etanercept produces rapid improvement in primary progressive aphasia: identification of a novel, rapidly reversible TNF-mediated pathophysiologic mechanisms. Tobinick E. Medscape Journal of Medicine, Neurology and Neurosurgery Clinical Cases 2008 June 10; 10(6):135. This video was included as part of the peer-reviewed, published, scientific article.
Video 5: Anti-TNF for Alzheimer's Disease produces rapid improvement*


This video is an interview with a family member discussing her family member's clinical response to initiation of perispinal etanercept at the INR. For the published results please see TNF-alpha Modulation for Treatment of Alzheimer's Disease: A 6-Month Pilot Study. Tobinick E, Gross H, Weinberger A, Cohen H. MedGenMed 2006; 8(2) :25 .
Downloadable videos: These versions are in a different format from the Flash® videos above, and can be downloaded for viewing. Please click on the type of video which your computer is capable of viewing, and you will be brought to the INR webpage containing that video format. To insure optimal quality, all videos below require a wait for download or streaming.
Video 1: TNF-alpha modulation for Alzheimer's Disease video length 3+ minutes*

<Windows Media Video> <Quicktime Video>
Video 2: TNF-alpha modulation for Alzheimer's Disease video length 5 minutes*

<Windows Media Video>

(Note: This video requires Windows Media Player, available at www.microsoft.com/windows/windowsmedia/download/).
The videos above, available in different media formats, are interviews with family members discussing their family member's clinical response to initiation of anti-TNF treatment at the INR. For the published results please see TNF-alpha Modulation for Treatment of Alzheimer's Disease: A 6-Month Pilot Study. Tobinick E, Gross H, Weinberger A, Cohen H. MedGenMed 2006; 8(2) :25 .
Institute for Neurological Research, a private medical group, inc.
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Appointments and Information: (310) 824-6199

Copyright ©2008-9, the Institute for Neurological Research® (INR®), a private medical group, inc., all rights reserved. **U.S. patents 6,982,089 and 7,214,658, and additional issued and pending U.S. and foreign patents. These patents are assigned to TACT IP LLC. Please see the medical and legal disclaimer.

*Perispinal etanercept for Alzheimer's disease and other forms of dementia (the Tobinick Method™) is a patented, off-label treatment method developed at the INR.
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