TNF and Brain Dysfunction
TNF is an immune signaling molecule that initiates and amplifies the inflammatory response in a variety of organ systems. In addition, TNF serves a variety of functions related to the immune modulation of neuronal and brain function. Increasing evidence suggests that excess TNF may be associated with brain dysfunction. Excess TNF may exert its deleterious effects via a variety of mechanisms related to modulation of synaptic transmission and synaptic scaling. Clinical observations by INR physicians over a period of more than a decade have contributed to the understanding of the role of TNF-mediated pathophysiology in a variety of neuroinflammatory disorders.
Frequently Asked Questions
Q: How long has the INR been using its patented local anti-TNF treatment for patients? A: The INR has more than ten years experience using its patented local anti-TNF treatment for treating patients with neuroinflammatory disorders. Q: What is TNF? TNF is an immune signaling molecule that initiates and amplifies the inflammatory response in the human body. Q: How does etanercept work? Etanercept binds circulating TNF and thereby neutralizes the adverse effects of excess TNF.
An Alzheimer's Breakthrough
Rapid improvement in Alzheimer's, beginning within minutes of administration of the first dose of anti-TNF treatment, is a commonplace occurrence at the INR, as recently featured on 60 Minutes Australia (see http://sixtyminutes.ninemsn.com.au/stories/8360210/a-new-shot-at-life). Documentation and explanation of the physiologic basis for these unique treatment results has been made in a series of landmark scientific articles from the INR. The videos present on this website document the responses of actual INR patients to initiation and maintenance of anti-TNF treatment. Read more inside.